New Vaccine Platforms Tested in Mice: A Look at the Future of Medicine

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🧬 Why this matters

Did you know that some of today’s most promising vaccines are first tested in mice before moving on to human trials? Researchers are currently experimenting with next-generation vaccine platforms, aiming to provide better protection against emerging viruses, cancers, and autoimmune diseases.



🔬 Leading organizations and research institutes

Several world-class institutions are driving innovation:

NIH (National Institutes of Health, USA) – innovators in mRNA and protein-based vaccines.

Max Planck Institute (Germany) – developing nanoparticle-based vaccine delivery systems.

The University of Oxford (UK) – known for AstraZeneca’s COVID-19 vaccine – is now testing cancer vaccines in mice.

💡 Companies driving vaccine innovation


Biotech giants and startups are racing to the next breakthrough:

Moderna – testing mRNA-1345 vaccine for RSV.

BioNTech – expanding cancer immunotherapy with BNT122.

CureVac – improving second-generation mRNA vaccines.

Novavax – focusing on protein-based vaccines that could cost less than $20 per dose.

👩‍🔬 Scientists behind the research

Dr. Catalin Carico – Nobel Prize winner, pioneer of mRNA technology.

Dr. Ugur Sahin and Dr. Ozlem Turecci – co-founders of BioNTech, leading cancer vaccine research.

Dr Sarah Gilbert is the Oxford scientist behind the AstraZeneca vaccine.

💉 Examples of new vaccine platforms

Self-amplifying mRNA (saRNA) is more potent than standard mRNA.

Nanoparticle vaccines improve immune response, currently priced at less than $50 per dose in trials.

DNA vaccines are stable and cost-effective, with a projected price of $5–10 per dose.

💲 The cost factor

COVID-19 vaccines (Moderna/Pfizer): $20–30 per dose.

Experimental cancer vaccines: projected to cost over $1,000 per treatment cycle.

RSV and influenza vaccines: preliminary estimates range from $10 to $25 per dose.

🌍 What’s next?

Animal testing is just the beginning. If successful, these platforms could revolutionize global healthcare by making vaccines cheaper, faster to produce, and more adaptable to new threats.

👉 Curious about which vaccine could be the next game-changer?

Read more about Natural World 50 🌐

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